Andarine (S4): Uses, Dosage & Side Effect by Dr. Biljana Novkovic, Ph.D., which was last updated on April 7, 2019, is an essential article to users of Andarine. The article has significant information about Andarine. Andarine, commonly called S-4, is a renowned Selective Androgen Receptor Modulator (SARM) which is used by many people. Andarine is used to treat conditions such as prostate enlargement, osteoporosis, and muscle wasting. The modulator is also used by many bodybuilders and athletes to keep their bones active and avoid fractures.

The working of Andarine

The SARM works by binding itself to androgen receptors found in bone tissue and muscle only sparing the sensitive endocrine system and reproductive organs. The oral bioavailability is excellent in such a way that if taken orally, it bypasses the gastrointestinal system, and it’s absorbed directly by the blood.

Once it has been absorbed, it acts as fast as testosterone without the effects of estrogen and aromatization. However, for such best results, ensure to start with low doses as recommended. Once the body gets used, you can now update the amount you take — this aids in avoiding any possible side effects which would result from an overdose.

The Manufacturers

Andarine is manufactured by one of the biggest companies called GTX, Inc. GTX, Inc. is a pharmaceutical company which manufactures both SARMs and SERMs (selective estrogen receptor modulators). Andarine, which is referred to as GTx-007 by the company, is one of the best SARMs because it does not significantly affect the healthy body’s functioning negatively.

Animal Testing

  • GTX Inc. tested Andarine on animals, and it showed positive results. When the drug was administered to animals with benign prostatic hypertrophy, it reduced the weight of the prostate effectively. This test was a success because the animals’ muscle mass was not reduced, and also, no antiandrogenic side effect was encountered. Moreover, when tested on animals with weak bone muscles, the animals gained muscle mass, increased bone density, and regained strength.
  • This test was a success because the animals’ muscle mass was not reduced, and also, no antiandrogenic side effect was encountered. Moreover, when tested on animals with weak bone muscles, the animals gained muscle mass, increased bone density, and regained strength. These tests were mostly done on rats.

Mode of Action

Andarine is a SARM, which means it binds to the androgen receptor. Andarine has a high affinity to this receptor and in turn, acts like testosterone. Despite Andarine acting like testosterone, which plays the role of development of male reproductive tissues, this modulator does not affect the reproductive system. It only works on muscles and bones. This gives it an advantage over anabolic steroids which mess up many athletes.

Also, Andarine does not affect the endocrine system. Andarine is an oral drug, and once it is administered, it goes through the gastrointestinal system, and it is then absorbed into the bloodstream. Despite Andarine acting like testosterone, which plays the role of development of male reproductive tissues, this modulator does not affect the reproductive system. It only works on muscles and bones.

This gives it an advantage over anabolic steroids which mess up many athletes. Also, Andarine does not affect the endocrine system. Andarine is an oral drug, and once it is administered, it goes through the gastrointestinal system, and it is then absorbed into the bloodstream. After absorption, it binds to the androgen receptor, and the function begins.

Functions of Andarine

Functions of Andarine

As mentioned earlier, Andarine helps to increase bone density and muscles. Also, it helps in fat loss, and that is why many athletes prefer using it to other types of SARMs.

Bone Density

  • When tested on castrated male rats and in female rats whose ovaries were removed, Andarine proved to increase bone mineral density. Athletes who use Andarine show strength, and they have healthy bones. The modulator increases the affinity of bones to absorb proteins to the matrix, which increases the mineral density of the bone and in turn, increases strength.
  • Athletes who use Andarine show strength, and they have healthy bones. The modulator increases the affinity of bones to absorb proteins to the matrix, which increases the mineral density of the bone and in turn, increases strength. Many users use Andarine as they increase their bone density and strength substantially, and at the same time, they do not experience prostate enlargement, a problem experienced when using some steroids.

Increased Muscle Mass

  • The same rats which were used to test for increased bone density showed an increase in lean body mass. Andarine is used to prevent muscle wasting, and it has shown positive results in many users. The muscle growth in the rats was increased, and the same is experienced in humans. People who use Andarine to achieve a shredded look have proved that the drug works.
  • The muscle growth in the rats was increased, and the same is experienced in humans. People who use Andarine to achieve a shredded look have proved that the drug works. During the first week, a person experiences loss of water weight, and the muscles become stronger and harder. In addition to taking in Andarine, a user is advised to eat healthily, drink water, and exercise.

Losing Fat

  • The female rats which had no ovaries and were used in the tests also showed a significant decrease in fat. Therefore, this was proof that Andarine can also be used by people who are trying to lose fat. Some androgen receptors exist in the fat, and when Andarine binds with these receptors, fat oxidation is triggered. This will then significantly reduce fat in the body.

Side Effects of Andarine

Fortunately, no severe side effect of Andarine has recorded by users. This is because the main side effect of using steroids, which is increasing reproductive tissues is not a problem when using Andarine. However, it has been reported if a person uses the wrong dosage, which is higher than the recommended one, they might have slight vision problems.

  • They may have problems seeing at night as it causes yellow tint vision problems. Fortunately, the vision is wholly regained once the drug has been discontinued.
  • Andarine is one of the best SARMs for women to use. Many women use it, and they have not recorded any side effects with regards to their reproductive system and hormonal imbalance. They may have problems seeing at night as it causes yellow tint vision problems.
  • Fortunately, the vision is completely regained once the drug has been discontinued. Andarine is one of the best SARMs for women to use. Many women use it, and they have not recorded any side effects with regards to their reproductive system and hormonal imbalance.
  • Some people state that higher doses of Andarine can lead to mood swings and depression. However, this has not yet been proved. Therefore, it is vital to use the correct stated doses of Andarine to prevent these avoidable side effects.

Dosage of Andarine

Dosage of AndarineIt is a recommendation to start with a dosage of 25 to 50 mg per day, which is a lower dose. Later, the user can then go to 50 to 75 mg per day. However, women should stick to 25 mg per day. These dosages are taken twice a day, accompanied by a meal. When users purchase Andarine, it is essential to ask the chemist questions and ensure they have enough information about the drug before administering it into the body.

 

  • During animal testing, Andarine showed to have a half-life of about four to six hours. These dosages are taken twice a day, accompanied by a meal. When users purchase Andarine, it is vital to ask the chemist questions and ensure they have enough information about the drug before administering it into the body.
  • During animal testing, Andarine showed to have a half-life of about four to six hours. Therefore, it is useful to take one dose in the morning and another one during the day. These dosages can be purchased from any pharmacy in both capsule and syrup forms.
  • Andarine is an effective SARM which is appreciated by many users who have given positive reviews about it. This drug should only be used between eight to twelve weeks and then discontinued.
  • The user can then consider medical knowledge from a practitioner if they want to continue using it. However, it should also be accompanied by exercise and a healthy lifestyle for it to work effectively.

Unfortunately, Andarine has been listed on the World Anti-Doping Agency (WADA) prohibited list and the US Anti-Doping Agency (USADA) considers it as doping. Therefore, an athlete cannot use it if they compete or even months before the competition. The body should be free of Andarine for an athlete to compete.

Therefore, an athlete cannot use it if they are in competition or even months before the competition. The body should be free of Andarine for an athlete to compete. Andarine is an effective SARM for any athlete who wants to achieve muscle strength, fat loss, and healthy bone density. The article by Dr. Biljana Novkovicis educative, but it lacked supportive references.